Drug Interactions With Pemetrexed

HealthSavvy Sign In | Pemetrexed (Alimta®) can potentially interact with a few other medications. Some of the medicines that may lead to drug interactions with pemetrexed include:Nonsteroidal anti-inflammatory drugs (NSAIDs), such as: The following sections explain in detail the potentially negative interactions that can occur when pemetrexed is combined with any of the drugs listed above.Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)NSAIDs may decrease kidney function, which may increase the level of pemetrexed in the blood, thereby increasing the risk of side effects of pemetrexed. For people with normal kidney function, it is generally okay to combine pemetrexed with ibuprofen. For other NSAIDs, your healthcare provider may recommend that you avoid taking the NSAID for a specific period before and after each pemetrexed dosage. The exact period depends upon the particular NSAID.Check with your healthcare provider before combining any NSAID with pemetrexed. function createlink(url, title, index ) { var p=document.createElement("P"); p.setAttribute("onclick", "clickAnchor(event)" ); setClass( p, "chapterList" ); var a = document.createElement( "a"); a.style.color = "white"; var c = url.replace(/'/g, "'"); a.setAttribute("href", c ); a.innerHTML = title; p.appendChild( a ); return p; } function updateLinks() { var toc = document.getElementById("chapterTOC"); toc.innerHTML = ""; var p; p = createlink("#chapter_0","An Overview of Pemetrexed Interactions", status.index ); toc.appendChild( p ); p = createlink("#chapter_1","More Information on Drug Interactions With Pemetrexed", status.index ); toc.appendChild( p ); p = createlink("/pemetrexed/drug-interactions-with-pemetrexed-p2.html#chapter_2","Final Thoughts", status.index ); toc.appendChild( p ); } updateLinks(); function addToolbarButton(txt,divclass,hrefdest,onclickfunc,title,id) { var tb = document.getElementById("articleToolbar"); var td = document.createElement("TD"); if(id) td.setAttribute("id",id); var d = document.createElement("div"); setClass(d,divclass); d.onclick = function(e){ if (!onclickfunc||onclickfunc(e)!=false) {window.open(hrefdest,"_blank","");}}; d.setAttribute("title", title ); var href = document.createElement("A"); href.setAttribute("href", hrefdest ); href.onclick = onclickfunc; href.setAttribute("title", title ); href.innerHTML = txt; href.target = "_blank"; td.appendChild( d ); td.appendChild( href ); tb.appendChild(td); } function savvyClick(event) { createCookie("articleReferer",window.location + "|Drug Interactions With Pemetrexed",0,".emedtv.com"); urchinTracker("/savvyclick/http://mesothelioma.emedtv.com/pemetrexed/drug-interactions-with-pemetrexed.html"); var sc=readCookie("SAVVYLOGIN"); if (sc) { savvyAddTopic("Pemetrexed"); } else { grayWindow(); $('#logintext').html('Sign in to your HealthSavvy account to add this topic:'); document.forms['signinform1'].action='/savvy/loginAddTopicAndReturn.html'; document.forms['signinform1'].topicName="Pemetrexed"; domenu(event,'logininfo',0,-100,true,true,true); $('#email1').focus(); } return false;} function savvyAddTopic(str) { $.ajax({ url: "/savvy/ajaxAddTopic.txt?topic=Pemetrexed", success: function(data){if (data.substring(0,2)=="OK") {data = data.substring(2, data.length);$("#hs_savvy_favorite").css("display","none");}showMessageBox(data); }}); } function createToolbar() {var st=readCookie("SAVVYTOPCIS");if (!st || st.indexOf("|Pemetrexed|")==-1) {addToolbarButton("HealthSavvy", "tb_hsicon tool_sp", "#", savvyClick, "HealthSavvy","hs_savvy_favorite");} addToolbarButton("Share", "tb_face tool_sp", "http://www.facebook.com/sharer.php?u=http%3a%2f%2fmesothelioma.emedtv.com%2fpemetrexed%2fdrug-interactions-with-pemetrexed.html&t=Drug+Interactions+With+Pemetrexed", function() {urchinTracker("/facebookshare/http://mesothelioma.emedtv.com/pemetrexed/drug-interactions-with-pemetrexed.html");}, "Share on Facebook",null); addToolbarButton( "Share", "tb_twit tool_sp", "http://www.emedtv.com/twittershare.html?status=Currently+reading+Drug+Interactions+With+Pemetrexed+on+eMedTV%3a+http%3a%2f%2fmesothelioma.emedtv.com%2fpemetrexed%2fdrug-interactions-with-pemetrexed.html", function() {urchinTracker("/twittershare/http://mesothelioma.emedtv.com/pemetrexed/drug-interactions-with-pemetrexed.html");}, "Share on Twitter",null); addToolbarButton( "Email","tb_mail tool_sp", "#", function(event) {emailPage(event);return false;}, "Email Article",null); if ( window.external && typeof(window.external.AddFavorite) != "undefined" ) { addToolbarButton( "Add", "tb_favorite tool_sp", "#", function(event) {bookmarkPage(event);return false;}, "Bookmark Article",null); } addToolbarButton( "Print","tb_print tool_sp", "#", function(event) {printPage(event);return false;}, "Print Article",null); } createToolbar(); Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD Last reviewed by: Kristi Monson, PharmD var s = "Last" + " updated/reviewed: "; var lm = document.getElementById("lastmodified"); if ( lm ) { s += "October 27, 2009"; lm.innerHTML = s; }

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